You know, like Firestarter by the Prodigy.

Post some examples here and write a little explanation about how it changed everything.

I'll start: Smooth by Santana with Matchbox 20. Brought South American music to the masses by being an international pop smash. I mean, Santana's done alright and Matchbox 20 are a pretty big deal in the US, but who thought that not only would they work together, but they would put South America on the MAP?
https://www.youtube.com/watch?v=6Whgn_iE5uc